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| 1 - Lung, fibrinous inflammation, pleuritis - Gross |
The white shaggy material on the pleural surface of the lung is fibrin, formed from fibrinogen that leaked from the underlying vessels, due to increased vascular permeability, part of an acute inflammatory response.
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| 2 - Heart, fibrinous inflammation, pericarditis in uremia - Gross |
The pericardium should be shiny and smooth, but in this case, exudation of fibrinogen-containing fluid from vessels, due to increased permeability, has led to fibrin deposition.
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| 3 - Lung, fibrinous and hemorrhagic inflammation, pneumonia with fibrinous pleuritis - Very low power (Glass slide 41) |
- Pleural surfaces
This low-magnification view shows consolidation of the lung parenchyma in a case of lobar pneumonia (lung infection with acute inflammation). The pleural surface is identified for the purpose of orientation.
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| 4 - Lung, fibrinous and hemorrhagic inflammation, fibrinous pleuritis - High power (Glass slide 41) |
- Fibrinous exudate
- Macrophages
- Lung parenchyma
This is a high-power view of the fibrinous exudate covering the pleural surface. A few macrophages are present. These may engulf and digest the fibrin (resolution), or organization of the exudate may go on to produce a fibrous scar.
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| 5 - Lung, fibrinous and hemorrhagic inflammation, pneumonia - Medium power (Glass slide 41) |
- Alveolar septal walls
- Normal lung
In the lung parenchyma, the normally empty alveolar spaces are filled with leukocytes and pink fibrin.
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