Monday, July 23, 2012

Inflammation and Repair 1 Outline (part-2) In Pathologic Basis Of Disease





6 - Lung, fibrinous and hemorrhagic inflammation, pneumonia - High power (Glass slide 41)
  • Congested capillaries in alveolar walls
  • Erythrocytes
At this higher power, the nature of the inflammatory exudate is clearer. It consists of erythrocytes that have leaked out of the very permeable and congested capillaries, thin strands of fibrin derived from fibrinogen in the exuded plasma, and leukocytes that have exited the vessels via diapedesis. 

7 - Hand, purulent inflammation, staphylococcal abscess - Clinical presentation
  • Abscess
Inflammation involving a dense neutrophilic infliltrate is called purulent (referring to pus) or suppurative. A localized collection of neutrophils, necrotic cells, and edema fluid (pus) in tissue is an abscess. Collections of neutrophils tend to have a greenish-yellow or whitish-yellow color, as seen here.


8 - Trachea, bronchi and lungs, purulent inflammation, bronchopneumonia and abscess - Gross, cut surface
  • Abscess
  • Purulent inflammation 

Note the pale yellow color of the area of purulent inflammation. In one focus, this inflammation has formed an abscess.







9 - Lung, purulent inflammation, abscess - Very low power (Glass slide 46)

  • Abscesses
In this section of the lung, the large, irregularly shaped defects lined by shaggy, basophilic material are abscesses. They appear empty, because the liquid purulent material washed away when the tissue was sectioned to prepare the slide. The remaining parenchyma appears consolidated.

10 - Lung, purulent inflammation, abscess - High power (Glass slide 46)
This high-power view of the wall of the abscess demonstrates the dense neutrophilic infiltrate.

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